Can pH control the brain?
The easiest way to see this is probably to test the thesis from the endpoints. Let’s say that the cell volume of the brain to 40% consists of gill cells and that some of them have the capability to regulate pH in the brain, what will then happen if they stop doing that? Or if they are forced to do it cause a lack of substrate.
Or if the proton is the main switch in any organisms driven by proton motive force, then what happens if we change the balance for example ad some extracellular H+. Would the mechanism or substance that control the pH of the pH controller in the brain controls the function of the brain?
Well if our cellular life are based on proton gradients isn’t our consciousness is based on protons then? The difference of the extracellular and intracellular controls much of the life potential, then the gradient and order and the Ionic order will control the longevity. Does it sounds reasonable since up to 20-80% of the cellular resting metabolic rate is required to redistribute ions through Na+ / K+-ATP-dependent pumping system. (Rolfe and Brand, 1996; Priebe et al., 1996; Rolfe and Brown, 1997).
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